Recombinant Mouse Ephrin-A5/EFNA5 Protein (His Tag)

Specifications

Catalog number

PKSM041010-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Ephrin-A5 is a glycosylphosphatidylinositol (GPI) -anchored protein of the ephrin-A subclass of ephrin ligands that binds to the EphA subclass of Eph receptors. Ephrin-A5 has also been shown to bind to the EphB2 receptor. It is crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Ephrin-A5 binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.

Abbreviation

Ephrin-A5; EFNA5

Synonyms

AL-1; EPH-related receptor tyrosine kinase ligand 7; Efna5; Ephrin-A5; Epl7; Eplg7; Lerk7

UniProt

O08543

Accession Number

O08543

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gln21-Gln206

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

22.5 kDa

Observed Molecular Weight

25-28 kDa

Species

Mouse