Recombinant Mouse FSTL1 Protein (Fc Tag)

Specifications

Catalog number

PKSM041026-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Follistatin-like 1 (FSTL1) is a secreted glycoprotein that has been grouped into the follistatin family of proteins. FSTL1 is composed of a follistatin domain and two non-functional calcium-binding motifs. It was originally cloned as a TGFβ1 inducible factor but subsequently shown to regulate diverse developmental pathways and tissue homeostasis. Ablation of the FSTL1 gene in the mouse results in several structural developmental defects and neonatal lethality due to respiratory failure. FSTL1 suppresses BMP signaling, but the precise mechanism of its action has not been elucidated. FSTL1 is expressed in the human placenta, mainly in extravillous trophoblasts.

Abbreviation

FSTL1

Synonyms

Follistatin-like protein 1; Follistatin-related protein 1; Fstl1; TGF-beta-inducible protein TSC-36

UniProt

Q62356

Accession Number

Q62356

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Glu19-Ile306

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

59.6 kDa

Observed Molecular Weight

70-85 kDa

Species

Mouse