Recombinant Mouse Frizzled 1/FZD1 Protein (Fc Tag)

Specifications

Catalog number

PKSM041027-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Frizzled homolog 1 (FZD1), also known as Frizzled-1, a member of the G-protein-coupled receptor superfamily, mediates Wnt signaling by serving as a co-receptor with LRP-5 for Wnt ligands. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif.

Abbreviation

Frizzled 1; FZD1

Synonyms

Frizzled homolog 1; Frizzled-1; Fz-1; Fzd1; mFz1

UniProt

O70421

Accession Number

O70421

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Val69-His248

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

46.8 kDa

Observed Molecular Weight

55-70 kDa

Species

Mouse