Recombinant Mouse Glypican-1/GPC1 Protein (His Tag)

Specifications

Catalog number

PKSM041030-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Glypican-1 is a cell membrane protein and belongs to the glypican family. The protein may act as a catalyst in increasing the rate of conversion of prion protein PRPN (C) to PRNP (Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. It is required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling.

Abbreviation

Glypican-1; GPC1

Synonyms

Glypican-1; Gpc1

UniProt

Q9QZF2

Accession Number

Q9QZF2

Expression System

HEK293 Cells

Tag

C-His

Sequence

Asp24-Ser529

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

56.7 kDa

Observed Molecular Weight

56 kDa

Species

Mouse