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Product details

Recombinant Mouse IFNGR1 Protein (Fc Tag)

Catalog number PKSM041061-01

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Price for PKSM041061-01

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Size / count 10 µg

Specifications

Catalog number
PKSM041061-01
Size / count
10 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
The tetrameric receptor complex for IFNγ consists of two subunits, IFNGR1 (IFNγ Rα) and IFNGR2 (IFNγ Rβ), through which the dimeric IFN-γ exerts its biological functions, including antiviral, antiproliferation and immune-modulatory activity in mammals. Both IFNGR1 and IFNGR2 are single transmembrane proteins belonging to the class II cytokine family. FNGR1, widely expressed in most host cells, is essential for IFNγ binding, receptor trafficking, and signal transduction. IFNGR1 possesses an intracellular Janus tyrosine kinase (JAK) 1 binding site, a signal transducer and activator of transcription 1 (STAT1) binding site. The resulting STAT1 homodimers translocate from the cytoplasm to the nucleus and bind to the interferon-gamma activated sequence (GAS) promoter to induce expression of downstream interferon stimulated genes (ISGs) .
Abbreviation
IFNGR1
Synonyms
CD119; CD119 antigen; IFN gamma receptor 1; IFN-gamma receptor 1; IFN-gamma-R1; IFNGR; IFNGR1; Interferon gamma receptor 1; immune interferon receptor 1; interferon gamma receptor 1; interferon-gamma receptor alpha chain
UniProt
P15261
Accession Number
P15261
Expression System
HEK293 Cells
Tag
C-Fc
Sequence
Ala26-Asp253
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
53.0 kDa
Observed Molecular Weight
72-94 kDa
Species
Mouse

Frequently Asked Questions

What is the catalog number for Recombinant Mouse IFNGR1 Protein (Fc Tag)?

The catalog number for Recombinant Mouse IFNGR1 Protein (Fc Tag) is PKSM041061.

What sizes are available for Recombinant Mouse IFNGR1 Protein (Fc Tag)?

Recombinant Mouse IFNGR1 Protein (Fc Tag) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Mouse IFNGR1 Protein (Fc Tag) come in?

Recombinant Mouse IFNGR1 Protein (Fc Tag) is available in 2 different pack sizes.

Is Recombinant Mouse IFNGR1 Protein (Fc Tag) in stock?

Recombinant Mouse IFNGR1 Protein (Fc Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Mouse IFNGR1 Protein (Fc Tag)?

Recombinant Mouse IFNGR1 Protein (Fc Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Mouse IFNGR1 Protein (Fc Tag)?

Estimated delivery time for Recombinant Mouse IFNGR1 Protein (Fc Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Mouse IFNGR1 Protein (Fc Tag)?

The safety data sheet for Recombinant Mouse IFNGR1 Protein (Fc Tag) is available here: https://789.bio/eb/vT8qbD.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

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