Recombinant Mouse IFN-zeta/Limitin Protein (His Tag)

Specifications

Catalog number

PKSM041065-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Limitin, also called IFN-ζ, is a secreted interferon (IFN) -like glycoprotein. Limitin has approximately 30% sequence homology with IFN-α, IFN-β, and IFN-ω and binds to the IFN-α/β receptors. Like IFN-α and IFN-β, limitin has antiproliferative, immunomodulatory, and antiviral properties, it is unique in lacking influence on myeloid and erythroid progenitors. Similar dose requirement between limitin and IFN-α was observed for the enhancement of cytotoxic T lymphocyte activity, the augmentation of MHC class I expression, and the growth inhibition of a myelomonocytic leukemia cell line.

Abbreviation

IFN-zeta; Limitin

Synonyms

BGIF; IFN-z; IFN-zeta ; Ifnz; Limitin; Lmtn; interferon zeta

UniProt

Q9R1T0

Accession Number

Q9R1T0

Expression System

HEK293 Cells

Tag

C-His

Sequence

Leu22-Arg182

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

19.5 kDa

Observed Molecular Weight

19 kDa

Species

Mouse