Recombinant Mouse Lithostathine-2/REG2 Protein (His Tag)

Specifications

Catalog number

PKSM041102-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Regenerating protein 2 (Reg2) also known as Lithostathine 2, pancreatic thread protein (PTP2) and pancreatic stone protein 2 (PSP2), is a member of the Reg family of proteins. These small, secreted proteins have been implicated in a range of physiological processes including acting as acute phase reactants, lectins, survival/growth factors for insulin-producing pancreatic beta-cells, neural cells, and epithelial cells of the digestive system. Studies also indicate a role for Reg family members in tumor formation and indicate their potential for use as biomarkers of carcinogenesis. Mouse Reg2 is expressed in regenerating islets and normal exocrine pancreas. Reg2 also stimulates the growth of pancreatic beta cells. Mouse Reg2 belongs to the type II subclass of the Reg family and is the only subclass II Reg protein described.

Abbreviation

Lithostathine-2; REG2

Synonyms

Islet of Langerhans regenerating protein 2; PSP; PTP; Pancreatic stone protein 2; Pancreatic thread protein 2; Regenerating Islet-derived 2

UniProt

Q08731

Accession Number

Q08731

Expression System

HEK293 Cells

Tag

N-His

Sequence

Gln23-Ala173

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

17.7 kDa

Observed Molecular Weight

18 kDa

Species

Mouse