Recombinant Mouse LDHA/LDH1 Protein (His Tag)

Specifications

Catalog number

PKSM041103-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Mouse Lactate dehydrogenase A (LDHA) is a member of the LDH/MDH superfamily and LDH family. LDHA catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues, though predominantly in muscle tissue and tumours. It has also been shown that LDHA plays an important role in the development, invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria.

Abbreviation

LDHA; LDH1

Synonyms

L-lactate dehydrogenase; LDHA; Ldh1

UniProt

P06151

Accession Number

P06151

Expression System

HEK293 Cells

Tag

C-His

Sequence

Met1-Phe332

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

37.5 kDa

Observed Molecular Weight

37 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 50%Glycerol, 500 mMNaCl, 5% Trehalose, 5% Mannitol, 0.01% Tween 80, 1mM EDTA, pH9.0.

Species

Mouse