Recombinant Mouse MMP12/MMP-12/HME Protein (His Tag)

Specifications

Catalog number

PKSM041106-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Matrix metalloproteinase-12 (MMP12) is a secreted protein.It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. It can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.

Abbreviation

MMP12; MMP-12; HME

Synonyms

MME; MMP-12; Macrophage metalloelastase; Matrix metalloproteinase-12; Mme; Mmel; Mmp12

UniProt

P34960

Accession Number

P34960

Expression System

HEK293 Cells

Tag

C-His

Sequence

Ala29-Cys473

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

53.0 kDa

Observed Molecular Weight

64 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM PB, 500mM NaCl,0.01%Tween 80, 1mM EDTA, 50% Glycerol, pH6.0.

Species

Mouse