Recombinant Mouse S100A8/CAGA Protein (His Tag)

Specifications

Catalog number

PKSM041133-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Protein S100-A8 (Mrp8) contains 2 EF-hand domains and belongs to the S-100 family. Mrp8 binds two calcium ions per molecule with an affinity similar to that of the S-100 proteins. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. It may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis.

Abbreviation

S100A8; CAGA

Synonyms

60B8Ag; AI323541; B8Ag; CFAg; CP; Caga; Calgranulin-A; Chemotactic cytokine CP-10; Leukocyte L1 complex light chain; MRP-8; Migration inhibitory factor-related protein 8; Mrp8; Pro-inflammatory S100 cytokine; Protein S100-A8; S100 calcium-binding protein A8; S100a8

UniProt

P27005

Accession Number

P50115

Expression System

E.coli

Tag

C-His

Sequence

Met1-Glu89

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

11.3 kDa

Observed Molecular Weight

13 kDa

Species

Mouse