Recombinant Mouse SerpinF2/SERPINF2 Protein (Fc Tag)

Specifications

Catalog number

PKSM041142-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Alpha-2-antiplasmin, also called Serpin F2, is a serine protease inhibitor (serpin) responsible for inactivating plasmin, and an important enzyme participates in fibrinolysis and degradation of other proteins. In liver cirrhosis, there is decreased production of alpha 2-antiplasmin, leading to decreased inactivation of plasmin and an increase in fibrinolysis. Serpin F2 is major expressed on liver and kidney. Some other tissues such as muscle, intestine, central nervous system, and placenta also express Serpin F2 mRNA at a moderate level indicated that it is a key regulator of plasmin-mediated proteolysis in these tissues.

Abbreviation

SerpinF2; SERPINF2

Synonyms

Alpha-2-AP; Alpha-2-PI; Alpha-2-antiplasmin; Alpha-2-plasmin inhibitor; Serpin F2; Serpinf2

UniProt

Q61247

Accession Number

Q61247

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Val28-Lys491

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

79.3 kDa

Observed Molecular Weight

90-120 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 20% Glycerol, pH 8.0.

Species

Mouse