Recombinant Mouse Testican-3/SPOCK3 Protein (His Tag)

Specifications

Catalog number

PKSM041154-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Testican3, also called SPOCK3, is a secreted protein and make up a family of extracellular heparan/chondroitin sulfate proteoglycans. It contains 1 Kazal-like domain and 1 thyroglobulin type-1 domain. Testican3 contain inhibitory regions in several domains targeted to different classes of protease, and in some cases may act as protease inhibitors. In addition to their presence in testis, testicans are enriched in brain and have been shown to regulate neuronal attachment and outgrowth. It may participate in diverse steps of neurogenesis and Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. It also may interfere with tumor invasion.

Abbreviation

Testican-3; SPOCK3

Synonyms

Spock3; Testican-3

UniProt

Q8BKV0

Accession Number

Q8BKV0-1

Expression System

HEK293 Cells

Tag

C-His

Sequence

Ala23-Ile436

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

47.9 kDa

Observed Molecular Weight

58-60 kDa

Species

Mouse