Recombinant Mouse TSLP Protein (Fc Tag)

Specifications

Catalog number

PKSM041159-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Thymic stromal lymphopoietin (TSLP) is a protein belonging to the cytokine family, contains 140 amino acids. It is known to play an important role in the maturation of T cell populations through activation of antigen presenting cells. TSLP induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c+ dendritic cells. It can induce allergic inflammation by directly activating mast cells. TSLP is produced mainly by non-hematopoietic cells such as fibroblasts, epithelial cells and different types of stromal or stromal-like cells. These cells are located in regions where TSLP activity is required.

Abbreviation

TSLP

Synonyms

TSLP; Thymic stroma-derived lymphopoietin; Thymic stromal lymphopoietin; Tslp

UniProt

Q9JIE6

Accession Number

Q9JIE6

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Tyr20-Glu140

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

41.1 kDa

Observed Molecular Weight

42-58 kDa

Species

Mouse