Recombinant Mouse Cyclophilin A Protein

Specifications

Catalog number

PKSM041227-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Peptidyl-prolyl cis-trans isomerase A is a cytoplasm protein which belongs to the cyclophilin-type PPIase family and PPIase A subfamily. Cyclophilins (CyPs) are a family of proteins found in organisms ranging from prokaryotes to humans. These molecules exhibit peptidyl-prolyl isomerase activity, suggesting that they influence the conformation of proteins in cells. Cyclophilin A accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Cyclophilin A can interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.

Abbreviation

Cyclophilin A

Synonyms

CYPA ; Cyclophilin A; Cyclosporin A-binding protein; PPIA; PPIase A; Peptidyl-prolyl cis-trans isomerase A; Rotamase A; SP18

Accession Number

P17742

Expression System

E.coli

Tag

None

Sequence

Met1-Leu164

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

18.0 kDa

Observed Molecular Weight

16 kDa

Formulation

Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.

Species

Mouse