Recombinant Mouse Serpin F1/PEDF Protein

Specifications

Catalog number

PKSM041232-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Serpin F1 is secreted Neurotrophic protein and belongs to the serpin family. Serpin F1 Highly expressed in the liver, gastric glandular mucosa and renal tubules. It is also expressed in the brain, heart, lung retina and testes. It induces extensive neuronal differentiation in retinoblastoma cells. It is potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, exhibits no serine protease inhibitory activity.

Abbreviation

Serpin F1; PEDF

Synonyms

Caspin; Pedf; Pigment epithelium-derived factor; Sdf3; Serpin F1; Stromal cell-derived factor 3.

Accession Number

P97298

Expression System

E.coli

Tag

None

Sequence

Asp43-Thr417

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

42.0 kDa

Observed Molecular Weight

40 kDa

Formulation

Supplied as a 0.2 μm filtered solution of PBS, pH7.4.

Species

Mouse