Recombinant Mouse CD73/NT5E Protein (His Tag)

Specifications

Catalog number

PKSM041234-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Mouse CD73 is a glycosyl phosphatidylinositol (GPI) anchored membrane protein that belongs to the 5'-nucleotidase family. CD73 is an ecto 5'Nucleotidase expressed by most cell types. CD73 hydrolyzes extracellular nucleotides into membrane permeable nucleosides. CD73 is one of several enzymes responsible for the production of extracellular adenosine, a signaling molecule that is involved in responses to inflammation and tissue injury. CD73 is a lymphocyte maturation marker that has functions independent of its catalytic activity. CD73 is also a regulator of leukocyte extravasation, a function that requires its 5'Nucleotidase activity.CD73 has also been reported to regulate expression of pro-inflammatory molecules in mouse endothelium.

Abbreviation

CD73; NT5E

Synonyms

5'-NT;5'-nucleotidase; AI447961; CD73; Ecto-5'-nucleotidase; NT; Nt5 Protein; eNT

Accession Number

Q61503

Expression System

HEK293 Cells

Tag

C-His

Sequence

Trp29-Phe550

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

58.8 kDa

Observed Molecular Weight

60 kDa

Formulation

2

Species

Mouse