Recombinant Mouse VCAM1 Protein (Fc Tag)

Specifications

Catalog number

PKSM041260-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Vascular cell adhesion molecule 1 (VCAM-1) is a cell surface protein belonging to the immunoglobulin superfamily, the protein is expressed by activated endothelial cells and certain leukocytes (such as macrophages) . IL-1 beta, IL-4, TNF-alpha and IFN-gamma induced the expression of VCAM-1. The human and mouse VCAM-1 proteins share approximately 76% amino acid similarity. Mouse VCAM-1 is Important in cell-cell recognition. it appears to function in leukocyte-endothelial cell adhesion, and interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction.

Abbreviation

VCAM1

Synonyms

CD106; L1CAM; VCMA1; Vascular cell adhesion protein 1; Vcam-1; Vcam1

UniProt

P29533

Accession Number

P29533

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Phe25-Glu698

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

101.4 kDa

Observed Molecular Weight

100-130 kDa

Species

Mouse