Recombinant Mouse TROP2/TACSTD2 Protein (His Tag)

Specifications

Catalog number

PKSM041262-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Tumor-associated calcium signal transducer 2 (Tacstd2), also known as Cell surface glycoprotein Trop-2, belongs to the EPCAM family. Tacstd2 expressed in kidney, lung, ovary and testis and has high levels of expression in immortalized keratinocytes. Tacstd2 may functions as a growth factor receptor. It has negative regulation of branching involved in ureteric bud morphogenesis, cell motility, epithelial cell migration, ruffle assembly, stress fiber assembly and substrate adhesion-dependent cell spreading. Also, it has positive regulation of stem cell proliferation. Tacstd2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.

Abbreviation

TROP2; TACSTD2

Synonyms

C80403; Cell surface glycoprotein Trop-2; EGP-1; GA733-1; Ly97; TROP-2; Tacstd2; Trop2; Tumor-associated calcium signal transducer 2

UniProt

Q8BGV3

Accession Number

Q8BGV3

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gln25-Gly270

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

28.8 kDa

Observed Molecular Weight

38-55 kDa

Species

Mouse