Recombinant Mouse Trefoil Factor 3/TFF3 Protein (His Tag)

Specifications

Catalog number

PKSM041267-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Trefoil factors (TFF) are secretory products of mucin producing cells. They play a key role in the maintenance of the surface integrity of oral mucosa and enhance healing of the gastrointestinal mucosa by a process called restitution. TFF comprises the gastric peptides (TFF1), spasmolytic peptide (TFF2), and the intestinal trefoil factor (TFF3) . They have an important and necessary role in epithelial restitution within the gastrointestinal tract. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfide bonds. They are stable secretory proteins expressed in gastrointestinal mucosa. Trefoil Factor 3 (TFF3) is involved in the maintenance and repair of the intestinal mucosa. TFF3 promotes the mobility of epithelial cells in healing processes (motogen) .

Abbreviation

Trefoil Factor 3; TFF3

Synonyms

Intestinal trefoil factor; Itf; Tff3; Trefoil factor 3; mITF

UniProt

Q62395

Accession Number

Q62395

Expression System

HEK293 Cells

Tag

C-His

Sequence

Ala23-Phe81

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

7.3 kDa

Observed Molecular Weight

11 kDa

Species

Mouse