Recombinant Mouse Transferrin Receptor/TFRC Protein (His Tag) — image 1 of 3

Product details

Recombinant Mouse Transferrin Receptor/TFRC Protein (His Tag)

Q: What is the catalog number for Recombinant Mouse Transferrin Receptor/TFRC Protein (His Tag)?

The catalog number for Recombinant Mouse Transferrin Receptor/TFRC Protein (His Tag) is PKSM041270.

Q: What is the estimated delivery time for Recombinant Mouse Transferrin Receptor/TFRC Protein (His Tag)?

Estimated delivery time for Recombinant Mouse Transferrin Receptor/TFRC Protein (His Tag) is approximately 15 business day(s), depending on your location.

Q: Where can I find the safety data sheet (SDS/MSDS) for Recombinant Mouse Transferrin Receptor/TFRC Protein (His Tag)?

The safety data sheet for Recombinant Mouse Transferrin Receptor/TFRC Protein (His Tag) is available here: https://789.bio/eb/vbXPC8.

Q: What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Q: Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

Q: What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

Catalog number PKSM041270-01

Choose a variant (2 options)

Selecting a variant updates its price, size and availability.

Price for PKSM041270-01

Size / count 10 µg

Specifications

Catalog number: PKSM041270-01
Size / count: 10 µg
Dry ice: No
Hazardous: No
Discontinued: No
Background: Transferrin receptor protein 1 (TFRC) belongs to the peptidase M28 family that is synthesized as a 172 amino acid (aa) . TFRC regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. It binds one transferrin or HFE molecule per subunit and binds the HLA class II histocompatibility antigen, DR1. It Interacts with SH3BP3 and STEAP3, facilitates TFRC endocytosis in erythroid precursor cells. Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. It positively regulates T and B cell proliferation through iron uptake.
Abbreviation: Transferrin Receptor; TFRC
Synonyms: 2610028K12Rik; AI195355; AI426448; AU015758; CD71; E430033M20Rik; Mtvr-1; Mtvr1; TR; TfR; TfR1; Tfrc; Transferrin receptor protein 1; Trfr; p90
UniProt: Q62351
Accession Number: Q62351
Expression System: HEK293 Cells
Tag: N-His
Sequence: Cys89-Phe763
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Purity: > 95 % as determined by reducing SDS-PAGE.
Bioactivity: Not validated for activity
Reconstitution: Please refer to the printed manual for detailed information.
Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight: 77.0 kDa
Observed Molecular Weight: 90 kDa
Species: Mouse

Frequently Asked Questions

What is the catalog number for Recombinant Mouse Transferrin Receptor/TFRC Protein (His Tag)?

The catalog number for Recombinant Mouse Transferrin Receptor/TFRC Protein (His Tag) is PKSM041270.

What sizes are available for Recombinant Mouse Transferrin Receptor/TFRC Protein (His Tag)?

Recombinant Mouse Transferrin Receptor/TFRC Protein (His Tag) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Mouse Transferrin Receptor/TFRC Protein (His Tag) come in?

Recombinant Mouse Transferrin Receptor/TFRC Protein (His Tag) is available in 2 different pack sizes.

Is Recombinant Mouse Transferrin Receptor/TFRC Protein (His Tag) in stock?

Recombinant Mouse Transferrin Receptor/TFRC Protein (His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Mouse Transferrin Receptor/TFRC Protein (His Tag)?

Recombinant Mouse Transferrin Receptor/TFRC Protein (His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Mouse Transferrin Receptor/TFRC Protein (His Tag)?

Estimated delivery time for Recombinant Mouse Transferrin Receptor/TFRC Protein (His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Mouse Transferrin Receptor/TFRC Protein (His Tag)?

The safety data sheet for Recombinant Mouse Transferrin Receptor/TFRC Protein (His Tag) is available here: https://789.bio/eb/vbXPC8.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.