Recombinant Mouse PSGL-1/CD162 Protein (aa 42-307, Fc Tag)

Specifications

Catalog number

PKSM041283-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

P-selectin glycoprotein ligand 1 is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin.

Abbreviation

PSGL-1; CD162

Synonyms

CD162; CLA; PSGL-1; PSGL1; Psgl-1; Psgl1; Selp1

UniProt

Q62170

Accession Number

CAA62583.1

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Gln42-Cys307

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

54.7 kDa

Observed Molecular Weight

90 kDa

Species

Mouse