Recombinant Mouse IL-2RG/CD132 Protein (Fc Tag)

Specifications

Catalog number

PKSM041318-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

The Interleukin-2 receptor gamma chain (IL-2 Rγ, CD132) of the high affinity functional mouse IL-2 receptor complex is a member the hematopoietin receptor family. It is expressed on most lymphocyte (white blood cell) populations, and its gene is found on the X-chromosome of mammals. Common IL2 receptor-γ Chain is required for IL-2 receptor signaling. Besides IL-2, the Common IL2 receptor-γ chain has been shown to be a component of the functional receptor complexes for IL-4, IL-7, IL-9 and IL-15. It is a component of multiple cytokine receptors that are essential for lymphocyte development and function. Common IL2 receptor-γ Chain is also designated the common gamma chain.

Abbreviation

IL-2RG; CD132

Synonyms

IMD; IL2RG; CD132; CIDX; IL-2RG; IMD4; P64; SCIDX; SCIDX1; Cytokine receptor common subunit gamma; gammaC; Interleukin-2 receptor subunit gamma; common &gamma- chain-n; IL-2R&gamma

UniProt

Q3UPA9

Accession Number

Q3UPA9

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Ser25-Ala263

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

55.1 kDa

Observed Molecular Weight

80-100 kDa

Species

Mouse