Recombinant Mouse IL13RA1 Protein (Fc Tag)

Specifications

Catalog number

PKSM041321-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Interleukin-13 receptor subunit alpha-1 (IL-13RA1), also known as NR4, belongs to the hemopoietin receptor family. Interleukin-13 receptor is a complex of IL4R, IL13RA1, and possibly other components. It interacts with TRAF3IP1 and binds with low affinity to interleukin-13 (IL3) . IL-13RA1, together with IL4RA, can form a functional receptor for IL13. It also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. The WSXWS motif in domains appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.

Abbreviation

IL13RA1

Synonyms

IL-13 R alpha; Novel cytokine receptor; Interleukin-13 receptor subunit alpha; CD213a; IL-13RA; CD213a1; IL-13 R alpha 1; IL-13RA1; Interleukin-13 receptor subunit alpha-1; Interleukin-13-binding protein; Novel cytokine receptor 4; NR4; Il13r; Il13ra; Il13ra1; IL-13R&alpha-1-1; AI882074; IL-13r[a]

UniProt

O09030

Accession Number

O09030

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Ala25-Thr340

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

63.0 kDa

Observed Molecular Weight

80-120 kDa

Species

Mouse