Recombinant Mouse IMPAD1/IMP3 Protein (His Tag)

Specifications

Catalog number

PKSM041326-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

IMPAD1 protein (IMPA3, gPAPP or IMPase 3) belongs to the inositol monophosphatase family. It is found in Purkinje cells, brain stem, lung and chondrocytes. Mouse IMPAD1 gene encodes a type II transmembrane Golgi-embedded glycoprotein with 356 amino acid residues which generates a 306 amino acid residues mature protein after processing. It is expressed in embryo, and in theory may catalyze myo-inositol monophosphate to myo-inositol. Free myo-inositol is used to generate inositol phospholipid, an essential component of intracellular signaling pathways that mobilize calcium. Mouse IMPAD1 exhibits 91% sequence identity with the human homologue.

Abbreviation

IMPAD1; IMP3

Synonyms

IMPA3 ; Impad1; Inositol monophosphatase 3

UniProt

Q80V26

Accession Number

Q80V26

Expression System

HEK293 Cells

Tag

N-His

Sequence

Glu51-His356

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

34.3 kDa

Observed Molecular Weight

38 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5.

Species

Mouse