Recombinant Mouse TIM1/HAVCR1 Protein (His Tag)

Specifications

Catalog number

PKSM041333-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

TIM-1/KIM-1/HAVCR belongs to the immunoglobulin superfamily that cosisits 305 amino acid (aa) . It is expressed by stimulated T-cells. TIM-1/KIM-1/HAVCR may play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. And may have a role in kidney injury and repair. Belongs to the T-cell and airway phenotype regulator (Tapr) locus, a single chromosomal region that confers reduced T-helper type 2 responsiveness and protects against airway hyperactivity (AHR), the hallmark of human asthma.

Abbreviation

TIM1; HAVCR1

Synonyms

AI503787; HAVcr-1; Hepatitis A virus cellular receptor 1 homolog; KIM-1; Kidney injury molecule 1; T cell membrane protein 1; TIM-1; Timd1

UniProt

Q5QNS5

Accession Number

Q5QNS5

Expression System

HEK293 Cells

Tag

C-His

Sequence

Tyr22-Thr212

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

21.8 kDa

Observed Molecular Weight

35-50 kDa

Species

Mouse