Recombinant Mouse Hemopexin/HPX Protein (His Tag) — image 1 of 3

Product details

Recombinant Mouse Hemopexin/HPX Protein (His Tag)

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Catalog number PKSM041334-01

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Price for PKSM041334-01

Size / count 10 µg

Specifications

Catalog number: PKSM041334-01
Size / count: 10 µg
Dry ice: No
Hazardous: No
Discontinued: No
Background: Hemopexin (HPX) is plasma glycoprotein belongs to the family of the acute-phase proteins whose synthesis is induced after an inflammatory event. Hemopexin with two four-bladed beta -propeller folds has been found in other proteins including collagenases and provides sites for protein-protein interactions. The liver is the major synthesizing organ. Hemopexin participates in maintaining and recycling the iron pool by utilizing its high binding affinity toward heme composed of protoporphyrin IX and iron. It also functions in preventing oxidation caused by heme after hemolysis. Hydrophobic heme molecules can intercalate into lipid membranes and participate in the oxidation of lipid membrane components through the Fenton reaction resulting in lipid peroxidation. Hemopexin undergoes a conformational change upon the binding of heme. The conformational change allows hemopexin to interact with a specific receptor, forming a complex which is then internalized. Heme concentrations in plasma increase after hemolysis, which is associated with several pathological conditions such as reperfusion injury and ischemia.
Abbreviation: Hemopexin; HPX
Synonyms: Hemopexin; Hpx; Hpxn
UniProt: Q91X72
Accession Number: Q91X72
Expression System: HEK293 Cells
Tag: C-His
Sequence: Ser24-Gln460
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Purity: > 95 % as determined by reducing SDS-PAGE.
Bioactivity: Not validated for activity
Reconstitution: Not Applicable
Shipping Conditions: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight: 49.8 kDa
Observed Molecular Weight: 65-90 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, pH 5.5.
Species: Mouse

Product documents

Supporting information for this product.

Product Datasheet

Frequently Asked Questions

How do I request a quotation for this product?

Add the product and required quantity to your cart, then submit the quotation request from the checkout page. Include your contact and delivery details so the Afraxis team can respond.

How can I identify the product or variant I need?

Check the product description, specifications and catalogue number on this page. If the product has multiple variants, select the required catalogue number and size before adding it to your cart.

Where can I find product documentation?

Available product documents are listed in the Product documents section on this page. If a document you need is not listed, contact Afraxis and include the product name and catalogue number.

How do I check the price and availability?

The product page shows the available variant and any displayed price information. For a quotation or confirmation for your order, add the product to your cart and submit a request.

How long will delivery take?

Delivery timing depends on the product, supplier and destination. Request a quotation with your delivery details to confirm the expected timing for your order.

Does this product require special handling or shipping?

Review any product-specific handling details shown on this page. If you are unsure about storage or shipping requirements, contact Afraxis with the product name and catalogue number.

Who can use Afraxis products?

Afraxis products are supplied for laboratory and research use. Review the product documentation and intended-use information before use.

How do I contact Afraxis about this product?

Use the contact form or contact details on the Afraxis website. Include the product name and catalogue number so the team can assist with your enquiry.