Recombinant Mouse Galectin 9/LGALS9 Protein (GST Tag)

Specifications

Catalog number

PKSM041336-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin' s disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1.

Abbreviation

Galectin 9; LGALS9

Synonyms

Gal-9; Galectin-9; Lgals9

UniProt

O08573

Accession Number

O08573-2

Expression System

E.coli

Tag

N-GST

Sequence

Met1-Thr322

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 85 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

62.8 kDa

Observed Molecular Weight

58 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM PB, 1mM EDTA, 5mM β-Mercaptoethanol, 5% Trehalose, 400mM NaCl, pH6.5.

Species

Mouse