Recombinant Mouse NTPDase 2/ENTPD2 Protein (His Tag)

Specifications

Catalog number

PKSM041340-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD39L1 protein (ENTPD2 or NTPDase2) is a member of the ecto-nucleoside triphosphate diphosphohydrolase family which the main role is termination of purinergic signaling. CD39L1 gene encodes a precursor protein with 495 amino acid residues which generates a 437 amino acid residues mature protein after processing. It is an ecto-nucleotidase that found on the surface of vascular adventitial cells and accessory vascular cells. CD39L1 is a Ca2+- and Mg2+-dependent enzyme that activates platelets by preferentially converting ATP to ADP. CD39L1 plays a role in regulating thrombosis and inflammation which is considered to be a therapeutic target for thromboregulation and the treatment of vascular inflammation. Alternative splicing of CD39L1 gene results in multiple transcript variants.

Abbreviation

NTPDase 2; ENTPD2

Synonyms

Ecto-Nucleoside Triphosphate Diphosphohydrolase 2; Ectonucleoside triphosphate diphosphohydrolase 2; Entpd2

UniProt

O55026

Accession Number

O55026

Expression System

HEK293 Cells

Tag

C-His

Sequence

Cys26-Ser462

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

49.2 kDa

Observed Molecular Weight

63-90 kDa

Formulation

2

Species

Mouse