Recombinant Mouse AGR3 Protein (His Tag)

Specifications

Catalog number

PKSM041359-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Anterior gradient protein 3 (AGR3) is an 18 kDa member of the AGR family of proteins. It is expressed in the ciliated cells of the airway epithelium, not detected in the mucous cells. Mature human AGR3 shares 92% amino acid sequence identity with mouse AGR3. It is required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. AGR3 might be involved in the regulation of intracellular calcium in tracheal epithelial cells.

Abbreviation

AGR3

Synonyms

AG3; AGR3; Anterior gradient protein 3; BCMP11

UniProt

Q8R3W7

Accession Number

Q8R3W7

Expression System

HEK293 Cells

Tag

C-His

Sequence

Ile21-Leu165

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

18.1 kDa

Observed Molecular Weight

15-19 kDa

Formulation

Supplied as a 0.2 μm filtered solution of PBS, 50% Glycerol, pH7.4.

Species

Mouse