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Product details

Recombinant Mouse TRAIL R2/TNFRSF10B Protein (AVI & His Tag)

Catalog number PKSM041369-01

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Price for PKSM041369-01

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Size / count 20 µg

Specifications

Catalog number
PKSM041369-01
Size / count
20 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Mouse tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) is a member of the TNFR family which contains 1 death domain and 3 TNFR-Cys repeats. TNFRSF10B exhibits high structural and functional homology to TRAIL-R1 (DR-4) . TNFRSF10B is highly expressed in heart, lung, lymphocytes, spleen and kidney. In addition, it is regulated by the tumor suppressor p53. TNFRSF10B is the receptor for the cytotoxic ligand TNFSF10/TRAIL. It promotes the activation of NF-kappa-B and is essential for ER stress-induced apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases mediating apoptosis.
Abbreviation
TRAIL R2; TNFRSF10B
Synonyms
CD262; DR5; Death Receptor 5; KILLER; TNF-Related Apoptosis-Inducing Ligand Receptor 2; TNFRSF10B; TRAIL Receptor 2; TRAIL-R2; TRAILR2; TRICK2; Tumor Necrosis Factor Receptor Superfamily Member 10B; ZTNFR9
UniProt
Q9QZM4
Accession Number
Q9QZM4
Expression System
HEK293 Cells
Conjugation
Biotinylated
Tag
C-Avi-His
Sequence
Asn53-Ser177
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
16.4 kDa
Observed Molecular Weight
20-40 kDa
Species
Mouse

Frequently Asked Questions

What is the catalog number for Recombinant Mouse TRAIL R2/TNFRSF10B Protein (AVI & His Tag)?

The catalog number for Recombinant Mouse TRAIL R2/TNFRSF10B Protein (AVI & His Tag) is PKSM041369.

What sizes are available for Recombinant Mouse TRAIL R2/TNFRSF10B Protein (AVI & His Tag)?

Recombinant Mouse TRAIL R2/TNFRSF10B Protein (AVI & His Tag) is available in the following size(s): 20 µg, 100 µg.

How many pack sizes does Recombinant Mouse TRAIL R2/TNFRSF10B Protein (AVI & His Tag) come in?

Recombinant Mouse TRAIL R2/TNFRSF10B Protein (AVI & His Tag) is available in 2 different pack sizes.

Is Recombinant Mouse TRAIL R2/TNFRSF10B Protein (AVI & His Tag) in stock?

Recombinant Mouse TRAIL R2/TNFRSF10B Protein (AVI & His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Mouse TRAIL R2/TNFRSF10B Protein (AVI & His Tag)?

Recombinant Mouse TRAIL R2/TNFRSF10B Protein (AVI & His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Mouse TRAIL R2/TNFRSF10B Protein (AVI & His Tag)?

Estimated delivery time for Recombinant Mouse TRAIL R2/TNFRSF10B Protein (AVI & His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Mouse TRAIL R2/TNFRSF10B Protein (AVI & His Tag)?

The safety data sheet for Recombinant Mouse TRAIL R2/TNFRSF10B Protein (AVI & His Tag) is available here: https://789.bio/eb/vX588C.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

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