Recombinant Mouse IL-2 Receptor Subunit Beta/IL-2RB/CD122 (C-Fc)

Specifications

Catalog number

PKSM041435-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

IL-2RB, also known asinterleukin-2 receptor subunit beta, is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein, and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs.

Abbreviation

IL-2RB; CD122

Synonyms

CD122; High affinity IL-2 receptor subunit beta; IL15Rbeta; IL-15Rbeta; IL-2 receptor subunit beta; Il-2/15Rbeta; IL-2R subunit beta; IL-2RB; Il-2Rbeta; Interleukin-2 receptor subunit beta; p70; p70-75; Il2rb; IL-2Rβ IL15RB; Interleukin-15 receptor subunit beta; p75

UniProt

P16297

Accession Number

P16297

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Ala27-Glu240

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

52.2 kDa

Observed Molecular Weight

70-110 kDa

Species

Mouse