Recombinant Mouse IL-7 protein (His Tag)

Specifications

Catalog number

PKSM041462-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

IL7, also known as interleukin 7, is a hematopoietic growth factor that belongs to the IL-7/IL-9 family. It is secreted by stromal cells in the bone marrow and thymus. IL7 stimulates the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. IL7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. It is found to be a cofactor for V (D) J rearrangement of the T cell receptor beta (TCRß) during early T cell development. IL7 can be produced locally by intestinal epithelial and epithelial goblet cells and may serve as a regulatory factor for intestinal mucosal lymphocytes.

Abbreviation

IL-7

Synonyms

Lymphopoietin; IL-7 interleukin; IL-7 interleukin-7; Interleukin-7; Lymphopoietin -1; PBGF; Il-7; Il7

UniProt

P10168

Accession Number

P10168

Expression System

E.coli

Tag

C-His

Sequence

Glu 26-Ile 154

Applications

Cell culture

Endotoxin

< 0.1 EU per μg of the protein as determined by the LAL method.

Purity

> 98 % as determined by reducing SDS-PAGE.

Bioactivity

50 5 x 106 IU/mg.6

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

15.8 kDa

Observed Molecular Weight

16 kDa

Species

Mouse