Recombinant Mouse IL-28B protein (His Tag)

Specifications

Catalog number

PKSM041474-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Interleukin-28B; also known as Cytokine Zcyto22; Interferon lambda-3; Interferon lambda-4; IFNL3; IFNL4; ZCYTO22 and IL28B; is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition; IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.

Abbreviation

IL-28B

Synonyms

Cytokine Zcyto; IL-12 subunit p; ZCYTO; Cytokine Zcyto22; Cytotoxic Lymphocyte Maturation Factor 35 kDa; IFNL4; IFN-Lambda-3; IFN-Lambda-4; IL-12 subunit p35; IL-12A; IL-28B; IL28C; IL-28C; Interferon Lambda-3; Interferon Lambda-4; Interleukin-12 subunit alpha; Interleukin-28B; Interleukin-28C; ZCYTO22; Il28; Il28b; Ifnl3

UniProt

Q8CGK6

Accession Number

Q8CGK6

Expression System

E.coli

Tag

C-His

Sequence

Asp 20-Val 193

Applications

Cell culture

Endotoxin

< 0.1 EU per μg of the protein as determined by the LAL method.

Purity

> 98 % as determined by reducing SDS-PAGE.

Bioactivity

50

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

20.6 kDa

Observed Molecular Weight

17-25 kDa

Species

Mouse