Recombinant Mouse IL-17B protein (His Tag)

Specifications

Catalog number

PKSM041494-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Interleukin-17B (IL-17B) is a member of IL-17 cytokines family that plays important roles in host defence responses and inflammatory diseases. In addition to IL-17B, members of the IL-17 family include IL-17A, IL-17C, IL-17D, IL-17E and IL-17F. The six IL-17 cytokines are highly conserved at C terminus, and contain five spatially conserved cysteine residues that mediate dimerization. Expression of IL-17B protein has been reported in neurons, testis, ovary, stomach, pancreas, small intestine and chondrocytes. IL-17B binds to Interleukine-17 receptor B (IL-17 RB) and induces the production of inflammatory cytokines and the infiltration of inflammatory immune cells.

Abbreviation

IL-17B

Synonyms

Zcyto; hlb38; hlb382; LTalpha; Ltx; lymph; Lymphotoxin-alpha (LT-α) ; Tnf; Tnfb; TNF-be; Tnfsf; TNFSF1; TNFSF1B; Tnlg1e; Nirf; Zcyto7; Il17b; Tnfb; Tnfsf

UniProt

Q9QXT6

Accession Number

Q9QXT6

Expression System

E.coli

Tag

C-His

Sequence

His 21-Phe 180

Applications

Cell culture

Endotoxin

< 0.1 EU per μg of the protein as determined by the LAL method.

Purity

> 98 % as determined by reducing SDS-PAGE.

Bioactivity

50

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

19.0 kDa

Observed Molecular Weight

17-25 kDa

Species

Mouse