Recombinant Cynomolgus OX40/TNFRSF4 Protein (His Tag)

Specifications

Catalog number

PKSQ050014-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

LYN contains one protein kinase domain, one SH2 domain, one SH3 domain, and the protein kinase domain plays an important role in its localization in the cell membrane. LYN is also thought to participate in signal transduction from cell surface receptors that lack intrinsic tyrosine kinase activity. In addition, LYN is associated with a number of cell surface receptors including the B cell antigen receptor and immunoglobulin E receptor (FceRI) .

Abbreviation

OX40; TNFRSF4

Synonyms

Lck/Yes-related novel protein tyrosine kinase; Tyrosine-protein kinase Lyn (LYN) ; V-yes-1 Yamaguchi sarcoma viral related oncogene homolog; p53Lyn; p56Lyn and JTK8

UniProt

P07948

Accession Number

XM_005545122.1

Expression System

HEK293 Cells

Tag

C-His

Sequence

Lys28-Ala214

Field of Research

Signal Transduction

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

21.3 kDa

Observed Molecular Weight

35-50 kDa

Species

Cynomolgus macaques