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Product details

Recombinant Cynomolgus Interleukin-4 Receptor Subunit Alpha/IL-4 Rα Protein (His Tag)

Catalog number PKSQ050053-01

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Size / count 10 µg

Specifications

Catalog number
PKSQ050053-01
Size / count
10 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Interleukin-4 receptor subunit alpha (IL-4RA), alos known as Soluble IL-4 receptor subunit alpha, belongs to the type I cytokine receptor family and type 4 subfamily. It expressed in both Th1 and Th2 cells. It functions as receptor for both interleukin 4 and interleukin 13 and couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and chemokine and mucus production at sites of allergic inflammation. In certain cell types, IL-4RA can signal through activation of insulin receptor substrates, IRS1/IRS2. The functional IL4 receptor is formed by initial binding of IL4 to IL4R. Subsequently it recruits to the complex of the common gamma chain. In immune cells, IL-4RA creates a type I receptor. In non-immune cells, it forms a type II receptor with of IL13RA1. IL4R can also interact with the IL13/IL13RA1 complex to form a similar type II receptor and interacts with the SH2-containing phosphatases, PTPN6/SHIP1, PTPN11/SHIP2 and INPP5D/SHIP.
Abbreviation
IL-4RA
Synonyms
CD124; IL-4R-alpha; IL-4RA; IL4-BP; Interleukin-4 receptor subunit alpha; Soluble IL-4R-alpha
UniProt
G7Q0S7
Accession Number
G7Q0S7
Expression System
HEK293 Cells
Tag
C-His
Sequence
Met26-Arg232
Applications
Cell culture
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
50
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
24.6 kDa
Observed Molecular Weight
38-58 kDa
Species
Cynomolgus macaques

Frequently Asked Questions

What is the catalog number for Recombinant Cynomolgus Interleukin-4 Receptor Subunit Alpha/IL-4 Rα Protein (His Tag)?

The catalog number for Recombinant Cynomolgus Interleukin-4 Receptor Subunit Alpha/IL-4 Rα Protein (His Tag) is PKSQ050053.

What sizes are available for Recombinant Cynomolgus Interleukin-4 Receptor Subunit Alpha/IL-4 Rα Protein (His Tag)?

Recombinant Cynomolgus Interleukin-4 Receptor Subunit Alpha/IL-4 Rα Protein (His Tag) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Cynomolgus Interleukin-4 Receptor Subunit Alpha/IL-4 Rα Protein (His Tag) come in?

Recombinant Cynomolgus Interleukin-4 Receptor Subunit Alpha/IL-4 Rα Protein (His Tag) is available in 2 different pack sizes.

Is Recombinant Cynomolgus Interleukin-4 Receptor Subunit Alpha/IL-4 Rα Protein (His Tag) in stock?

Recombinant Cynomolgus Interleukin-4 Receptor Subunit Alpha/IL-4 Rα Protein (His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Cynomolgus Interleukin-4 Receptor Subunit Alpha/IL-4 Rα Protein (His Tag)?

Recombinant Cynomolgus Interleukin-4 Receptor Subunit Alpha/IL-4 Rα Protein (His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Cynomolgus Interleukin-4 Receptor Subunit Alpha/IL-4 Rα Protein (His Tag)?

Estimated delivery time for Recombinant Cynomolgus Interleukin-4 Receptor Subunit Alpha/IL-4 Rα Protein (His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Cynomolgus Interleukin-4 Receptor Subunit Alpha/IL-4 Rα Protein (His Tag)?

The safety data sheet for Recombinant Cynomolgus Interleukin-4 Receptor Subunit Alpha/IL-4 Rα Protein (His Tag) is available here: https://789.bio/eb/zHuDiT.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

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