Recombinant HIV Recombinant HIV gp120 Protein (His Tag)

Specifications

Catalog number

PKSQ050061-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Envelope glycoprotein gp160 is single-pass type I membrane protein. The mature envelope protein (Env) consists of a homotrimer of non-covalently associated gp120-gp41 heterodimers. It is cleaved into the following 2 chains: glycoprotein 120 and transmembrane protein gp41. The resulting complex protrudes from the virus surface as a spike. The 17 amino acids long immunosuppressive region is present in many retroviral envelope proteins. Synthetic peptides derived from this relatively conserved sequence inhibit immune function in vitro and in vivo.

Abbreviation

Gp120

Synonyms

Envelope glycoprotein gp120; Glycoprotein 120; Surface protein gp120

UniProt

Q9DKG6

Accession Number

Q9DKG6

Expression System

HEK293 Cells

Tag

C-His

Sequence

Met1-Glu498

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

57.0 kDa

Observed Molecular Weight

90-140 kDa

Species

HIV