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Product details

Recombinant Rhesus macaque B7-H4/VTCN1 Protein (His Tag)

Catalog number PKSQ050083-01

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Price for PKSQ050083-01

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Size / count 10 µg

Specifications

Catalog number
PKSQ050083-01
Size / count
10 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. It also involved in promoting epithelial cell transformation.
Abbreviation
B7-H4; VTCN1
Synonyms
B7-H4; B7H4T-cell costimulatory molecule B7x; B7S1; B7S1VCTN1; B7XPRO1291; B7h.5; B7x; FLJ22418; Immune costimulatory protein B7-H4; Protein B7S1; T cell costimulatory molecule B7x; V-set domain containing T cell activation inhibitor 1; V-set domain-containing ; Vtcn1
UniProt
F7B770
Accession Number
F7B770
Expression System
HEK293 Cells
Tag
C-His
Sequence
Phe29-Ala258
Applications
BLI
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Loaded Recombinant Rhesus Macaque B7-H4 on HIS1K Biosensor, can bind Human B7-H4 mAb with an affinity constant of 0.578 pM as determined in BLI assay.
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
26.4 kDa
Observed Molecular Weight
40-60 kDa
Species
Rhesus macaque

Frequently Asked Questions

What is the catalog number for Recombinant Rhesus macaque B7-H4/VTCN1 Protein (His Tag)?

The catalog number for Recombinant Rhesus macaque B7-H4/VTCN1 Protein (His Tag) is PKSQ050083.

What sizes are available for Recombinant Rhesus macaque B7-H4/VTCN1 Protein (His Tag)?

Recombinant Rhesus macaque B7-H4/VTCN1 Protein (His Tag) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Rhesus macaque B7-H4/VTCN1 Protein (His Tag) come in?

Recombinant Rhesus macaque B7-H4/VTCN1 Protein (His Tag) is available in 2 different pack sizes.

Is Recombinant Rhesus macaque B7-H4/VTCN1 Protein (His Tag) in stock?

Recombinant Rhesus macaque B7-H4/VTCN1 Protein (His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Rhesus macaque B7-H4/VTCN1 Protein (His Tag)?

Recombinant Rhesus macaque B7-H4/VTCN1 Protein (His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Rhesus macaque B7-H4/VTCN1 Protein (His Tag)?

Estimated delivery time for Recombinant Rhesus macaque B7-H4/VTCN1 Protein (His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Rhesus macaque B7-H4/VTCN1 Protein (His Tag)?

The safety data sheet for Recombinant Rhesus macaque B7-H4/VTCN1 Protein (His Tag) is available here: https://789.bio/eb/m1yzbT.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

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