Recombinant Cynomolgus FGL1 (C-Avi-6His) Biotinylated

Specifications

Catalog number

PKSQ050098-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Fibrinogen-like protein 1 (FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3.

Abbreviation

FGL1

Synonyms

FGL1; Fibrinogen-like protein 1; HFREP-1; HP-041; Hepassocin; LFIRE-1

UniProt

A0A2K5X990

Accession Number

A0A2K5X990

Expression System

HEK293 Cells

Conjugation

Biotinylated

Tag

C-Avi-His

Sequence

Leu23-Ile312

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

34.8 kDa

Observed Molecular Weight

36 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 300mM NaCl, 10% Glycerol, 2mM EDTA, pH 8.0.

Species

Cynomolgus macaques