Recombinant Cynomolgus IL-4 Receptor Subunit Alpha/IL-4RA (C-Fc)

Q: What is the catalog number for Recombinant Cynomolgus IL-4 Receptor Subunit Alpha/IL-4RA (C-Fc)?

The catalog number for Recombinant Cynomolgus IL-4 Receptor Subunit Alpha/IL-4RA (C-Fc) is PKSQ050100.

Q: What is the estimated delivery time for Recombinant Cynomolgus IL-4 Receptor Subunit Alpha/IL-4RA (C-Fc)?

Estimated delivery time for Recombinant Cynomolgus IL-4 Receptor Subunit Alpha/IL-4RA (C-Fc) is approximately 15 business day(s), depending on your location.

Q: Where can I find the safety data sheet (SDS/MSDS) for Recombinant Cynomolgus IL-4 Receptor Subunit Alpha/IL-4RA (C-Fc)?

The safety data sheet for Recombinant Cynomolgus IL-4 Receptor Subunit Alpha/IL-4RA (C-Fc) is available here: https://789.bio/eb/zbnnjP.

Q: What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Q: Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Q: Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Catalog number PKSQ050100-01

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Price for PKSQ050100-01

Size / count 10 µg

Specifications

Catalog number: PKSQ050100-01
Size / count: 10 µg
Dry ice: No
Hazardous: No
Discontinued: No
Background: Interleukin-4 receptor subunit alpha (IL-4RA), alos known as Soluble IL-4 receptor subunit alpha, belongs to the type I cytokine receptor family and type 4 subfamily. It expressed in both Th1 and Th2 cells. It functions as receptor for both interleukin 4 and interleukin 13 and couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and chemokine and mucus production at sites of allergic inflammation. In certain cell types, IL-4RA can signal through activation of insulin receptor substrates, IRS1/IRS2. The functional IL4 receptor is formed by initial binding of IL4 to IL4R. Subsequently it recruits to the complex of the common gamma chain. In immune cells, IL-4RA creates a type I receptor. In non-immune cells, it forms a type II receptor with of IL13RA1. IL4R can also interact with the IL13/IL13RA1 complex to form a similar type II receptor and interacts with the SH2-containing phosphatases, PTPN6/SHIP1, PTPN11/SHIP2 and INPP5D/SHIP.
Abbreviation: IL-4RA
Synonyms: CD124; IL-4R-alpha; IL-4RA; IL4-BP; Interleukin-4 receptor subunit alpha; Soluble IL-4R-alpha
UniProt: G7Q0S7
Accession Number: G7Q0S7
Expression System: HEK293 Cells
Tag: C-Fc
Sequence: Met26-Arg232
Applications: Cell culture
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Purity: > 95 % as determined by reducing SDS-PAGE.
Bioactivity: 50
Reconstitution: Please refer to the printed manual for detailed information.
Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight: 50.7 kDa
Observed Molecular Weight: 65-90 kDa
Species: Cynomolgus macaques

Frequently Asked Questions

What is the catalog number for Recombinant Cynomolgus IL-4 Receptor Subunit Alpha/IL-4RA (C-Fc)?

The catalog number for Recombinant Cynomolgus IL-4 Receptor Subunit Alpha/IL-4RA (C-Fc) is PKSQ050100.

What sizes are available for Recombinant Cynomolgus IL-4 Receptor Subunit Alpha/IL-4RA (C-Fc)?

Recombinant Cynomolgus IL-4 Receptor Subunit Alpha/IL-4RA (C-Fc) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Cynomolgus IL-4 Receptor Subunit Alpha/IL-4RA (C-Fc) come in?

Recombinant Cynomolgus IL-4 Receptor Subunit Alpha/IL-4RA (C-Fc) is available in 2 different pack sizes.

Is Recombinant Cynomolgus IL-4 Receptor Subunit Alpha/IL-4RA (C-Fc) in stock?

Recombinant Cynomolgus IL-4 Receptor Subunit Alpha/IL-4RA (C-Fc) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Cynomolgus IL-4 Receptor Subunit Alpha/IL-4RA (C-Fc)?

Recombinant Cynomolgus IL-4 Receptor Subunit Alpha/IL-4RA (C-Fc) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Cynomolgus IL-4 Receptor Subunit Alpha/IL-4RA (C-Fc)?

Estimated delivery time for Recombinant Cynomolgus IL-4 Receptor Subunit Alpha/IL-4RA (C-Fc) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Cynomolgus IL-4 Receptor Subunit Alpha/IL-4RA (C-Fc)?

The safety data sheet for Recombinant Cynomolgus IL-4 Receptor Subunit Alpha/IL-4RA (C-Fc) is available here: https://789.bio/eb/zbnnjP.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.