Recombinant Cynomolgus NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His) — image 1 of 3

Product details

Recombinant Cynomolgus NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His)

Q: What is the catalog number for Recombinant Cynomolgus NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His)?

The catalog number for Recombinant Cynomolgus NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His) is PKSQ050115.

Q: What is the estimated delivery time for Recombinant Cynomolgus NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His)?

Estimated delivery time for Recombinant Cynomolgus NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His) is approximately 15 business day(s), depending on your location.

Q: Where can I find the safety data sheet (SDS/MSDS) for Recombinant Cynomolgus NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His)?

The safety data sheet for Recombinant Cynomolgus NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His) is available here: https://789.bio/eb/eX1efL.

Q: What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

Q: What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

Q: How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Catalog number PKSQ050115-01

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Price for PKSQ050115-01

Size / count 10 µg

Specifications

Catalog number: PKSQ050115-01
Size / count: 10 µg
Dry ice: No
Hazardous: No
Discontinued: No
Background: NKG2-D type II integral membrane protein (NKG2D) is a type II transmembrane glycoprotein which belongs to the CD94/NKG2 family. NKG2D is expressed on natural killer (NK) cells, CD8+ alpha-beta and gamma-delta T-cells. As an activating and costimulatory receptor, it involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. It provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. It stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF-alpha. NKG2D participates in NK cell-mediated bone marrow graft rejection and survival of NK cells. It Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins including MICA, MICB, RAET1E, RAET1G, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4.
Abbreviation: NKG2D; CD314
Synonyms: CD314; CD314 antigen; KLR; KLRK1; Killer cell lectin-like receptor subfamily K member 1; NK cell receptor D; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NKG2D; killer cell lectin-like receptor subfamily K; member 1
UniProt: P61252
Accession Number: P61252
Expression System: HEK293 Cells
Tag: N-His
Sequence: Phe78-Val216
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Purity: > 95 % as determined by reducing SDS-PAGE.
Bioactivity: Not validated for activity
Reconstitution: Please refer to the printed manual for detailed information.
Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight: 16.9 kDa
Observed Molecular Weight: 22-35 kDa
Species: Cynomolgus macaques

Frequently Asked Questions

What is the catalog number for Recombinant Cynomolgus NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His)?

The catalog number for Recombinant Cynomolgus NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His) is PKSQ050115.

What sizes are available for Recombinant Cynomolgus NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His)?

Recombinant Cynomolgus NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Cynomolgus NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His) come in?

Recombinant Cynomolgus NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His) is available in 2 different pack sizes.

Is Recombinant Cynomolgus NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His) in stock?

Recombinant Cynomolgus NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Cynomolgus NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His)?

Recombinant Cynomolgus NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Cynomolgus NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His)?

Estimated delivery time for Recombinant Cynomolgus NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Cynomolgus NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His)?

The safety data sheet for Recombinant Cynomolgus NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His) is available here: https://789.bio/eb/eX1efL.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.