Recombinant Cynomolgus CD7/Leu-9 (C-6His)

Specifications

Catalog number

PKSQ050118-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

T-Cell Antigen CD7 is a single-pass type I membrane protein that that belongs to the the immunoglobulin superfamily. Human CD7 is synthesized as a 240 amino acid precursor that contains a 25 amino acid signal sequence and a 215 amino acid mature chain with a Ig-like (immunoglobulin-like) domain. CD7 is normally expressed on all T-lymphocytes, NK-cells, pre-B lymphocytes and pleuripotent hematopoietic stem cells. CD7 plays an essential role in T-cell interactions, T-cell/B-cell interaction during early lymphoid development, T- and NK-cell activation and cytokine production. CD7 has been shown to interact with PIK3R1and SECTM1. However, the function of the CD7 protein in the immune system is still largely unknown.

Abbreviation

CD7; Leu-9

Synonyms

CD7; GP40; T-Cell Antigen CD7; T-Cell Leukemia Antigen; T-Cell Surface Antigen Leu-9; TP41

UniProt

A0A2K5VA16

Accession Number

A0A2K5VA16

Expression System

HEK293 Cells

Tag

C-His

Sequence

Ala26-Pro180

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

17.2 kDa

Observed Molecular Weight

32 kDa

Species

Cynomolgus macaques