Recombinant Rat UNC5B/UNC5H2 Protein (Fc Tag)

Specifications

Catalog number

PKSR030375

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. In addition, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis.

Synonyms

UNC5B

UniProt

O08722

Accession Number

NP_071543.1

Expression System

HEK293 Cells

Tag

C-hFc

Sequence

Met1-Asp373

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 85 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

65.7 kDa

Observed Molecular Weight

72-90 kDa

Species

Rat