Recombinant Rat IL20RB Protein (His Tag)

Specifications

Catalog number

PKSR030418

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22) . Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family. IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20.

Abbreviation

IL20RB

Synonyms

UNQ; PRO; MGC; DIRS; FNDC; fibronectin type III domain containing; IL-20R; IL20RB; DIRS1; FNDC6; IL-20R2; fibronectin type III domain containing 6; hCG_2022374; IL-20 receptor subunit beta; IL-20RB; IL-20R-beta; interleukin-20 receptor II; Interleukin-20 receptor subunit beta; MGC34923; UNQ557; PRO1114

UniProt

B8K1X9

Accession Number

B8K1X9

Expression System

HEK293 Cells

Tag

C-His

Sequence

Met1-Pro227

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 91 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

24.6 kDa

Observed Molecular Weight

32-36 kDa

Species

Rat