Recombinant Human APN Protein (His Tag)

Specifications

Catalog number

PKSR030495-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

ANPEP gene encodes aminopeptidase N (APN) also known as microsomal aminopeptiase, alanyl aminopeptidase, aminopeptidase M, CD13, or membrane protein p161, is a member of the peptidase M1 family. Widely expressed in many cells, tissues and species, APN cleaves the N-terminal amino acids from bioactive peptides, leading to their inactivation or degradation. Probably plays a role in regulating growth and differentiation of early B-lineage cells. It also may play a role in the catabolic pathway of the renin-angiotensin system. It degrades vasoconstricting angiotensin II into angiotensin III and therefore helps to regulate blood pressure.

Abbreviation

APN

Synonyms

ANPEP; AP-M; AP-N; APN; Aminopeptidase N; CD13; CD13 antigen; CD13APN; PEPN; PEPNhAPN

UniProt

P15144

Accession Number

P15144

Expression System

HEK293 Cells

Tag

C-His

Sequence

Lys69-Lys967

Field of Research

Immunology; Stem cells

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

103.5 kDa

Observed Molecular Weight

110-130 kDa

Formulation

Supplied as a 0.2 μm filtered solution of PBS, 5% Trehalose, pH 7.4.

Species

Human