Recombinant SARS-CoV-2 NP (Truncated) (His Tag)

Specifications

Catalog number

PKSR030537

Size / count

1 mg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

Abbreviation

Nucleocapsid

Synonyms

2019-nCoV coronavirus NP Protein;2019-nCoV novel coronavirus Nucleoprotein Protein;2019-nCoV np Protein

UniProt

P0DTC2

Accession Number

QHD43423.2

Expression System

E.coli

Tag

N-His

Applications

ELISA

Endotoxin

Please contact us for more information.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Immobilized Recombinant 2019-nCoV NP (Truncated) at 2μg/ml (100 μl/well) can bind Anti-2019-nCoV NP Antibody (6G9), the ED50 for this effect is 4. 8 ng/ml.

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

36.2 kDa

Observed Molecular Weight

38 kDa

Formulation

Supplied as a 0.2 μm filtered solution of PBS, pH7.4.

Species

SARS-CoV-2