Recombinant Swine IL-1 alpha protein (His Tag)

Specifications

Catalog number

PKSS000001-01

Size / count

5 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Interleukin-1 alpha (IL1α) is a cytokine member of the interleukin-1 family. IL-1 consists of two distinct forms: IL1α and IL1β that recognize the same cell surface receptors but are distinct proteins with approximately 25% amino acid sequence identity. IL1α is constitutively produced by epithelial cells and plays an essential role in maintenance of skin barrier function. Upon stimulation, a wide variety of cells including osteoblasts, monocytes, macrophages can be induced to express IL1α. IL1α possesses a wide range of metabolic, physiological, haematopoietic activities, and is critically involved in the regulation of the immune responses and inflammatory responses.

Abbreviation

IL-1 alpha

Synonyms

Interleukin; Hematopoietin; IL1F1hematopoietin; IL1F; IL-1F; alpha; BAF; Hematopoietin-1; IL1; IL1 alpha; IL-1 alpha; IL1-A; IL-1A; IL1-ALPHA; IL1F1; IL-1F1; IL1F1hematopoietin-1; interleukin 1; interleukin-1 alpha; LAF; LEM; preinterleukin 1 alpha; pro-interleukin-1-alpha; Il1a; FAF; Hematopoietin 1; IL 1 alpha; IL 1A; IL1; IL1 ALPHA; IL1F1; Interleukin 1 alpha; LAF; LEM; Preinterleukin 1 alpha; Il1a

UniProt

P18430

Accession Number

P18430

Expression System

E.coli

Tag

C-His

Sequence

Ser113-Ser270

Applications

Cell culture

Endotoxin

< 0.1 EU per μg of the protein as determined by the LAL method.

Purity

> 98 % as determined by reducing SDS-PAGE.

Bioactivity

50

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

19.0 kDa

Observed Molecular Weight

17-25 kDa

Species

Porcine