Recombinant SARS-CoV-2 NP CTD domain V2 (C-6His)

Specifications

Catalog number

PKSV030279

Size / count

1 mg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may beinvolved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packagesthe positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role duringvirion assembly through its interactions with the viral genome and membrane protein M. Plays an important rolein enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of theconservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as adiagnostic tool.

Abbreviation

Nucleocapsid

Synonyms

2019-nCoVcoronavirusNPProtein;2019-nCoVnovelcoronavirusNucleoprotein Protein;2019-nCoVnpProtein

UniProt

P0DTC2

Accession Number

QHD43423.2

Expression System

E.coli

Tag

N-His

Sequence

Thr247-Pro364

Endotoxin

Please contact us for more information.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

17.1 kDa

Observed Molecular Weight

17 kDa

Formulation

Supplied as a 0.2 μM filtered solution of 50mM PB, 150mM NaCl, 1mM EDTA, pH 7.4

Species

SARS-CoV-2