Anti-ERK 5 MAPK7 Antibody

Catalog number A02812-2

Discontinued

Price for A02812-2

Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

Boster Bio Anti-ERK 5 MAPK7 Antibody catalog # A02812-2. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A02812-2
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Synonyms: Mitogen-activated protein kinase 7; MAP kinase 7; MAPK 7;2.7.11.24; Big MAP kinase 1; BMK-1; Extracellular signal-regulated kinase 5; ERK-5; MAPK7; BMK1, ERK5, PRKM7;
Gene Name: MAPK7
UniProt: Q13164
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant Protein
Clonality: Polyclonal
Tissue Specificity: Expressed in many adult tissues. Abundant in heart, placenta, lung, kidney and skeletal muscle. Not detectable in liver.
Applications: WB, IHC
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Form: Liquid
Function: Plays a role in various cellular processes such as proliferation, differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through a Ras- independent and MAP2K5-dependent pathway. May have a role in muscle cell differentiation. May be important for endothelial function and maintenance of blood vessel integrity. MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression. Involved in the regulation of p53/TP53 by disrupting the PML-MDM2 interaction.
Molecular Weight: 88386 MW
Shipping Conditions: Available
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment: IgG
Other Gene Names: Mitogen-activated protein kinase 7
Subcellular Location: Cytoplasm. Nucleus. Nucleus, PML body. Translocates to the nucleus upon activation.
Protein Name: Mitogen-activated protein kinase 7

Frequently Asked Questions

What is the catalog number for Anti-ERK 5 MAPK7 Antibody?

The catalog number for Anti-ERK 5 MAPK7 Antibody is A02812-2.

Is Anti-ERK 5 MAPK7 Antibody in stock?

Anti-ERK 5 MAPK7 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-ERK 5 MAPK7 Antibody?

The safety data sheet for Anti-ERK 5 MAPK7 Antibody is available here: https://www.bosterbio.com/msds?sku=A02812-2.

What is Anti-ERK 5 MAPK7 Antibody used for?

Boster Bio Anti-ERK 5 MAPK7 Antibody catalog # A02812-2. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.