Anti-Collagen alpha-1 (XII) chain COL12A1 Antibody

About this product

Boster Bio Anti-Collagen alpha-1 (XII) chain COL12A1 Antibody catalog # A05008-1. Tested in ELISA, WB applications. This antibody reacts with Human.

Specifications

Catalog number

A05008-1

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

Synonyms

Collagen alpha-1 (XII) chain; COL12A1; COL12A1L;

Gene Name

COL12A1

UniProt

Q99715

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide from human COL12A1 protein.

Clonality

Polyclonal

Tissue Specificity

Found in collagen I-containing tissues: both isoform 1 and isoform 2 appear in amnion, chorion, skeletal muscle, small intestine, and in cell culture of dermal fibroblasts, keratinocytes and endothelial cells. Only isoform 2 is found in lung, placenta, kidney and a squamous cell carcinoma cell line. Isoform 1 is also present in the corneal epithelial Bowman's membrane (BM) and the interfibrillar matrix of the corneal stroma, but it is not detected in the limbal BM.

Applications

WB, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix. .

Molecular Weight

333147 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Collagen alpha-1 (XII) chain

Subcellular Location

Secreted, extracellular space, extracellular matrix .

Protein Name

Collagen alpha-1 (XII) chain